Levodopa Quick Facts

Levodopa is a precursor to dopamine. It is use, along with carbidopa, in the treatment of PD. Levodopa alone is not longer used to treat PD.

Carbidopa/levodopa can be found under the brand name Sinemet®. It is available in doses of 10/100, 25/100, or 25/250 milligrams in a treatment regimen typically total between 150-1,000 milligrams divided 3-4 times per day.

Carbidopa/levodopa extended release, found under the brand name Sinemet CR®, is available in presentations of 25/100 and 50/200 milligrams in a treatment regimen usually between 150-1,000 milligrams divided 3-4 times per day.

An oral disentigrating presentation of carbidopa/levodopa, found under the brand name Parcopa®, is available in presentations of 10/100, 25/100 and 25/200 milligrams. The treatment regimen is usually between 150-1,000 milligrams divided 3-4 times per day.

Carbidopa/levodopa/entacapone can be found under the brand name Stalevo®. It is available in doses of 12.5/50/200, 18.75/75/200, 25/100/200, 31.25/125/200, 37.5/150/200 and 50/200/200 milligrams and typical treatment regimens vary between 150-1,000 milligrams of levodopa total dose divided 3-4 times per day. Entacapone is a COMT-inhibitor that increases bioavailability of levodopa.

See the levodopa and COMT-inhibitors pages for more information: